Fabrication of multi-parametric platforms based on nanocone arrays for determination of cellular response

• Lindarti Purwaningsih,
• Tobias Schoen,
• Tobias Wolfram,
• Claudia Pacholski and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2011, 2, 545–551, doi:10.3762/bjnano.2.58

• nanocones with gold tips. By using a combination of block copolymer nanolithography, electroless deposition, and reactive ion etching several parameters such as structure height and structure distance could easily be adjusted to the desired values. The gold tips allow for easy functionalization of the

• finding for research dealing with the reactions of neuron-like tissue in the immediate moments after direct contact with an implanted surface. Keywords: block copolymer nanolithography; cell adhesion; nanostructures; surface chemistry; surface topography; Introduction Nanostructured materials for

• on nanocones is approximately 40% higher compared to flat gold nanoparticles. Method used to fabricate silica nanocone arrays with gold functionalized tips. A quasi-hexagonally ordered gold nanoparticle array was deposited on a silica substrate by block copolymer nanolithography (a). Electroless